Synthesis, characterization and antimicrobial activity of some carbamothioyl-1,3,4- thiadiazole derivatives

A series of 5-substituted-2-phenyl-1, 3, 4-thiadiazole were prepared by the reaction of different substituted benzoylisothiocyanate with 5-amino -2-phenyl -1, 3, 4-thiadiazole. The target molecules were characterized by CHNS analysis, IR, NMR and mass spectra. All these new compounds were screened for antibacterial and antifungal activity. Some of those compounds had promising antimicrobial activity.